Enantiospecific Synthesis of ortho-Substituted Benzylic Boronic Esters by a 1,2-Metalate Rearrangement/1,3-Borotropic Shift Sequence

[Image: see text] Coupling reactions between benzylamines and boronic esters have been investigated. ortho-Lithiated benzylamines react with boronic esters and a N-activator to afford ortho-substituted benzylic boronic esters with formal 1,1′-benzylidene insertion into the C–B bond. The reaction occ...

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Detalles Bibliográficos
Autores principales: Aichhorn, Stefan, Bigler, Raphael, Myers, Eddie L., Aggarwal, Varinder K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520102/
https://www.ncbi.nlm.nih.gov/pubmed/28661133
http://dx.doi.org/10.1021/jacs.7b05880

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520102/
https://www.ncbi.nlm.nih.gov/pubmed/28661133
http://dx.doi.org/10.1021/jacs.7b05880

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