CBF1 is clinically prognostic and serves as a target to block cellular invasion and chemoresistance of EMT-like glioblastoma cells

BACKGROUND: Glioblastoma is the most common and most lethal primary brain cancer. CBF1 (also known as Recombination signal Binding Protein for immunoglobulin kappa J, RBPJ) is the cardinal transcriptional regulator of the Notch signalling network and has been shown to promote cancer stem-like cells...

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Detalles Bibliográficos
Autores principales: Maciaczyk, D, Picard, D, Zhao, L, Koch, K, Herrera-Rios, D, Li, G, Marquardt, V, Pauck, D, Hoerbelt, T, Zhang, W, Ouwens, D M, Remke, M, Jiang, T, Steiger, H J, Maciaczyk, J, Kahlert, U D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520214/
https://www.ncbi.nlm.nih.gov/pubmed/28571041
http://dx.doi.org/10.1038/bjc.2017.157

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520214/
https://www.ncbi.nlm.nih.gov/pubmed/28571041
http://dx.doi.org/10.1038/bjc.2017.157

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