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Identification of differential co-expressed gene networks in early rheumatoid arthritis achieving sustained drug-free remission after treatment with a tocilizumab-based or methotrexate-based strategy

BACKGROUND: Methotrexate is endorsed to be used as first-line treatment in rheumatoid arthritis (RA). However, a large proportion of patients need additional treatment with a biological disease-modifying anti-rheumatic drug (DMARD) to adequately suppress their disease activity. A better understandin...

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Detalles Bibliográficos
Autores principales: Teitsma, Xavier M., Jacobs, Johannes W. G., Mokry, Michal, Borm, Michelle E. A., Pethö-Schramm, Attila, van Laar, Jacob M., Bijlsma, Johannes W. J., Lafeber, Floris P. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520225/
https://www.ncbi.nlm.nih.gov/pubmed/28728565
http://dx.doi.org/10.1186/s13075-017-1378-x