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Identification of differential co-expressed gene networks in early rheumatoid arthritis achieving sustained drug-free remission after treatment with a tocilizumab-based or methotrexate-based strategy
BACKGROUND: Methotrexate is endorsed to be used as first-line treatment in rheumatoid arthritis (RA). However, a large proportion of patients need additional treatment with a biological disease-modifying anti-rheumatic drug (DMARD) to adequately suppress their disease activity. A better understandin...
Autores principales: | Teitsma, Xavier M., Jacobs, Johannes W. G., Mokry, Michal, Borm, Michelle E. A., Pethö-Schramm, Attila, van Laar, Jacob M., Bijlsma, Johannes W. J., Lafeber, Floris P. J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520225/ https://www.ncbi.nlm.nih.gov/pubmed/28728565 http://dx.doi.org/10.1186/s13075-017-1378-x |
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