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Reduced glutathione and glutathione disulfide in the blood of glucose-6-phosphate dehydrogenase-deficient newborns

BACKGROUND: Glucose-6-phosphate dehydrogenase (G6PD) deficiency is commonly detected during mass screening for neonatal disease. We developed a method to measure reduced glutathione (GSH) and glutathione disulfide (GSSG) using tandem mass spectrometry (MS/MS) for detecting G6PD deficiency. METHODS:...

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Detalles Bibliográficos
Autores principales: Gong, Zhen-hua, Tian, Guo-li, Huang, Qi-wei, Wang, Yan-min, Xu, Hong-ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520230/
https://www.ncbi.nlm.nih.gov/pubmed/28728551
http://dx.doi.org/10.1186/s12887-017-0920-y