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AHRR (cg05575921) hypomethylation marks smoking behaviour, morbidity and mortality

RATIONALE AND OBJECTIVES: Self-reported smoking underestimates disease risk. Smoking affects DNA methylation, in particular the cg05575921 site in the aryl hydrocarbon receptor repressor (AHRR) gene. We tested the hypothesis that AHRR cg05575921 hypomethylation is associated with risk of smoking-rel...

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Detalles Bibliográficos
Autores principales: Bojesen, Stig E, Timpson, Nicholas, Relton, Caroline, Davey Smith, George, Nordestgaard, Børge G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520281/
https://www.ncbi.nlm.nih.gov/pubmed/28100713
http://dx.doi.org/10.1136/thoraxjnl-2016-208789