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A novel preventive strategy against HIV-1 infection: combinatorial use of inhibitors targeting the nucleocapsid and fusion proteins

The strategy of simultaneously attacking multiple targets is worthy of exploration in the field of microbicide development to combat HIV-1 sequence diversity and minimize the transmission of resistant variants. A combination of S-acyl-2-mercaptobenzamide thioester-10 (SAMT10), an inhibitor of the HI...

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Detalles Bibliográficos
Autores principales: Yang, Yu, Zhu, Jingyu, Hassink, Matthew, Jenkins, Lisa M Miller, Wan, Yanmin, Appella, Daniel H, Xu, Jianqing, Appella, Ettore, Zhang, Xiaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520304/
https://www.ncbi.nlm.nih.gov/pubmed/28588284
http://dx.doi.org/10.1038/emi.2017.26