Cargando…

Differences in sequences between HBV-relaxed circular DNA and covalently closed circular DNA

The hepatitis B virus (HBV) genome exists in two forms: circular covalently closed DNA (cccDNA) and relaxed circular DNA (RCDNA). Here, we investigated the presence of differences in the sequences of both forms in paired samples of serum and liver tissue. The serum and liver biopsy samples were coll...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rybicka, Magda, Woziwodzka, Anna, Romanowski, Tomasz, Stalke, Piotr, Dręczewski, Marcin, Bielawski, Krzysztof Piotr
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520316/ https://www.ncbi.nlm.nih.gov/pubmed/28634352 http://dx.doi.org/10.1038/emi.2017.41

Ejemplares similares

TNF‐α polymorphisms affect persistence and progression of HBV infection
por: Woziwodzka, Anna, et al.
Publicado: (2019)

Liver Cirrhosis in Chronic Hepatitis B Patients Is Associated with Genetic Variations in DNA Repair Pathway Genes
por: Rybicka, Magda, et al.
Publicado: (2020)

An initial assessment of correlations between host- and virus-related factors affecting analogues antiviral therapy in HBV chronically infected patients
por: Stalke, Piotr, et al.
Publicado: (2014)

Detection of HBV Covalently Closed Circular DNA
por: Li, Xiaoling, et al.
Publicado: (2017)

Conversion of hepatitis B virus relaxed circular to covalently closed circular DNA is supported in murine cells
por: Wei, Lei, et al.
Publicado: (2022)

HBV X protein mutations affect HBV transcription and association of histone-modifying enzymes with covalently closed circular DNA
por: Chong, Chun Kong, et al.
Publicado: (2020)

The role of host DNA ligases in hepadnavirus covalently closed circular DNA formation
por: Long, Quanxin, et al.
Publicado: (2017)

Forkhead O Transcription Factor 4 Restricts HBV Covalently Closed Circular DNA Transcription and HBV Replication through Genetic Downregulation of Hepatocyte Nuclear Factor 4 Alpha and Epigenetic Suppression of Covalently Closed Circular DNA via Interacting with Promyelocytic Leukemia Protein
por: Li, Yuqi, et al.
Publicado: (2022)

Research progress in hepatitis B virus covalently closed circular DNA
por: Zhang, Xiaodong, et al.
Publicado: (2022)

Approaches to quantifying hepatitis B virus covalently closed circular DNA
por: Zhang, Henrik, et al.
Publicado: (2022)

A new model mimicking persistent HBV e antigen-negative infection using covalently closed circular DNA in immunocompetent mice
por: Wang, Lei, et al.
Publicado: (2017)

DNA Polymerase alpha is essential for intracellular amplification of hepatitis B virus covalently closed circular DNA
por: Tang, Liudi, et al.
Publicado: (2019)

Characterization of the Host Factors Required for Hepadnavirus Covalently Closed Circular (ccc) DNA Formation
por: Guo, Haitao, et al.
Publicado: (2012)

Dynamics of Hepatitis B Virus Covalently Closed Circular DNA: A Mini-Review
por: Hu, Jie-Li, et al.
Publicado: (2023)

Association of Hepcidin mRNA Expression With Hepatocyte Iron Accumulation and Effects of Antiviral Therapy in Chronic Hepatitis C Infection
por: Sikorska, Katarzyna, et al.
Publicado: (2014)

PCR mediated recombination impacts the analysis of hepatitis B Virus covalently closed circular DNA
por: Suspène, Rodolphe, et al.
Publicado: (2016)

New Insights on Molecular Mechanism of Hepatitis B Virus Covalently Closed Circular DNA Formation
por: Marchetti, Alexander L., et al.
Publicado: (2020)

Silencing hepatitis B virus covalently closed circular DNA: The potential of an epigenetic therapy approach
por: Singh, Prashika, et al.
Publicado: (2021)

A Novel Mouse Model Harboring Hepatitis B Virus Covalently Closed Circular DNA
por: Xu, Zaichao, et al.
Publicado: (2021)

CRISPR/Cas13-assisted hepatitis B virus covalently closed circular DNA detection
por: Zhang, Xiangying, et al.
Publicado: (2022)

Role of hepatitis B virus in development of hepatocellular carcinoma: Focus on covalently closed circular DNA
por: Bianca, Claryssa, et al.
Publicado: (2022)

Hepatitis B Virus Capsid: The Core in Productive Entry and Covalently Closed Circular DNA Formation
por: Mendenhall, Megan A., et al.
Publicado: (2023)

Analysis of Hepatitis B Virus Intrahepatic Covalently Closed Circular DNA and Serum Viral Markers in Treatment-Naive Patients with Acute and Chronic HBV Infection
por: Li, Weijie, et al.
Publicado: (2014)

LINC01431 Promotes Histone H4R3 Methylation to Impede HBV Covalently Closed Circular DNA Transcription by Stabilizing PRMT1
por: Sun, Yang, et al.
Publicado: (2022)

DNA Polymerase κ Is a Key Cellular Factor for the Formation of Covalently Closed Circular DNA of Hepatitis B Virus
por: Qi, Yonghe, et al.
Publicado: (2016)

Correction: Analysis of Hepatitis B Virus Intrahepatic Covalently Closed Circular DNA and Serum Viral Markers in Treatment-Naive Patients with Acute and Chronic HBV Infection
Publicado: (2014)

Hepatitis D, B and C virus (HDV/HBV/HCV) coinfection as a diagnostic problem and therapeutic challenge
por: Lorenc, Beata, et al.
Publicado: (2017)

Polymorphisms Related to Iron Homeostasis Associate with Liver Disease in Chronic Hepatitis C
por: Wróblewska, Anna, et al.
Publicado: (2023)

The Infection Efficiency and Replication Ability of Circularized HBV DNA Optimized the Linear HBV DNA in Vitro and in Vivo
por: Li, Xiaosong, et al.
Publicado: (2015)

Persistence of hepatitis B virus covalently closed circular DNA in hepatocytes: molecular mechanisms and clinical significance
por: Yang, Hung-Chih, et al.
Publicado: (2014)

Quantification of Pregenomic RNA and Covalently Closed Circular DNA in Hepatitis B Virus-Related Hepatocellular Carcinoma
por: Bai, Fugui, et al.
Publicado: (2013)

Role of Hepatitis B virus capsid phosphorylation in nucleocapsid disassembly and covalently closed circular DNA formation
por: Luo, Jun, et al.
Publicado: (2020)

Rapamycin inhibits hepatitis B virus covalently closed circular DNA transcription by enhancing the ubiquitination of HBx
por: Zhang, Yuan, et al.
Publicado: (2022)

Recent Advances in Understanding, Diagnosing, and Treating Hepatitis B Virus Infection
por: Rybicka, Magda, et al.
Publicado: (2020)

Potential capacity of interferon-α to eliminate covalently closed circular DNA (cccDNA) in hepatocytes infected with hepatitis B virus
por: Wang, Gang, et al.
Publicado: (2021)

Involvement of Host ATR-CHK1 Pathway in Hepatitis B Virus Covalently Closed Circular DNA Formation
por: Luo, Jun, et al.
Publicado: (2020)

Intracellular interferon signalling pathways as potential regulators of covalently closed circular DNA in the treatment of chronic hepatitis B
por: Goh, Zhi Yi, et al.
Publicado: (2021)

Functional cure of hepatitis B requires silencing covalently closed circular and integrated hepatitis B virus DNA
por: Ghany, Marc G., et al.
Publicado: (2022)

Hepatitis B Virus X Protein Stimulates Virus Replication Via DNA Methylation of the C-1619 in Covalently Closed Circular DNA
por: Lee, Hyehyeon, et al.
Publicado: (2019)

Transcription of Hepatitis B Virus Covalently Closed Circular DNA Is Regulated by CpG Methylation during Chronic Infection
por: Zhang, Yongmei, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_jrn1dkk4s8at6qst5mjisoi16c