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HIV-1 gp41-targeting fusion inhibitory peptides enhance the gp120-targeting protein-mediated inactivation of HIV-1 virions

Protein- or peptide-based viral inactivators are being developed as novel antiviral drugs with improved efficacy, pharmacokinetics and toxicity profiles because they actively inactivate cell-free human immunodeficiency virus type 1 (HIV-1) virions before attachment to host cells. By contrast, most c...

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Detalles Bibliográficos
Autores principales: Qi, Qianqian, Wang, Qian, Chen, Weizao, Du, Lanying, Dimitrov, Dimiter S, Lu, Lu, Jiang, Shibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520319/
https://www.ncbi.nlm.nih.gov/pubmed/28634358
http://dx.doi.org/10.1038/emi.2017.46