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Splicing arrays reveal novel RBM10 targets, including SMN2 pre-mRNA

BACKGROUND: RBM10 is an RNA binding protein involved in message stabilization and alternative splicing regulation. The objective of the research described herein was to identify novel targets of RBM10-regulated splicing. To accomplish this, we downregulated RBM10 in human cell lines, using small int...

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Detalles Bibliográficos
Autores principales: Sutherland, Leslie C., Thibault, Philippe, Durand, Mathieu, Lapointe, Elvy, Knee, Jose M., Beauvais, Ariane, Kalatskaya, Irina, Hunt, Sarah C., Loiselle, Julie J., Roy, Justin G., Tessier, Sarah J., Ybazeta, Gustavo, Stein, Lincoln, Kothary, Rashmi, Klinck, Roscoe, Chabot, Benoit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520337/
https://www.ncbi.nlm.nih.gov/pubmed/28728573
http://dx.doi.org/10.1186/s12867-017-0096-x