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Optimization of proximity ligation assay (PLA) for detection of protein interactions and fusion proteins in non-adherent cells: application to pre-B lymphocytes

BACKGROUND: Genetic abnormalities, including chromosomal translocations, are described for many hematological malignancies. From the clinical perspective, detection of chromosomal abnormalities is relevant not only for diagnostic and treatment purposes but also for prognostic risk assessment. From t...

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Detalles Bibliográficos
Autores principales: Debaize, Lydie, Jakobczyk, Hélène, Rio, Anne-Gaëlle, Gandemer, Virginie, Troadec, Marie-Bérengère
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520345/
https://www.ncbi.nlm.nih.gov/pubmed/28736577
http://dx.doi.org/10.1186/s13039-017-0328-2