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Cladosporol A triggers apoptosis sensitivity by ROS-mediated autophagic flux in human breast cancer cells

BACKGROUND: Endophytes have proven to be an invaluable resource of chemically diverse secondary metabolites that act as excellent lead compounds for anticancer drug discovery. Here we report the promising cytotoxic effects of Cladosporol A (HPLC purified >98%) isolated from endophytic fungus Clad...

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Detalles Bibliográficos
Autores principales: Koul, Mytre, Kumar, Ashok, Deshidi, Ramesh, Sharma, Vishal, Singh, Rachna D., Singh, Jasvinder, Sharma, Parduman Raj, Shah, Bhawal Ali, Jaglan, Sundeep, Singh, Shashank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520384/
https://www.ncbi.nlm.nih.gov/pubmed/28728544
http://dx.doi.org/10.1186/s12860-017-0141-0