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MicroRNA-26a and -26b inhibit lens fibrosis and cataract by negatively regulating Jagged-1/Notch signaling pathway

Fibrosis is a chronic process involving development and progression of multiple diseases in various organs and is responsible for almost half of all known deaths. Epithelial–mesenchymal transition (EMT) is the vital process in organ fibrosis. Lens is an elegant biological tool to investigate the fib...

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Detalles Bibliográficos
Autores principales: Chen, Xiaoyun, Xiao, Wei, Chen, Weirong, Liu, Xialin, Wu, Mingxing, Bo, Qu, Luo, Yan, Ye, Shaobi, Cao, Yihai, Liu, Yizhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520447/
https://www.ncbi.nlm.nih.gov/pubmed/28622289
http://dx.doi.org/10.1038/cdd.2016.152