Physiological Concentrations of Amyloid Beta Regulate Recycling of Synaptic Vesicles via Alpha7 Acetylcholine Receptor and CDK5/Calcineurin Signaling

Despite the central role of amyloid β (Aβ) peptide in the etiopathogenesis of Alzheimer’s disease (AD), its physiological function in healthy brain is still debated. It is well established that elevated levels of Aβ induce synaptic depression and dismantling, connected with neurotoxicity and neurona...

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Detalles Bibliográficos
Autores principales: Lazarevic, Vesna, Fieńko, Sandra, Andres-Alonso, Maria, Anni, Daniela, Ivanova, Daniela, Montenegro-Venegas, Carolina, Gundelfinger, Eckart D., Cousin, Michael A., Fejtova, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520466/
https://www.ncbi.nlm.nih.gov/pubmed/28785201
http://dx.doi.org/10.3389/fnmol.2017.00221

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520466/
https://www.ncbi.nlm.nih.gov/pubmed/28785201
http://dx.doi.org/10.3389/fnmol.2017.00221

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