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A new model of self-resolving leptospirosis in mice infected with a strain of Leptospira interrogans serovar Autumnalis harboring LPS signaling only through TLR4

Leptospirosis is an emerging worldwide zoonosis caused by pathogenic Leptospira spp. Our understanding of leptospirosis pathogenesis and host immune response remains limited, while mechanistic studies are hindered by a lack of proper animal models and immunological reagents. Here we established a mu...

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Detalles Bibliográficos
Autores principales: Xia, Bili, Sun, Le, Fan, Xia, Xiao, Haihan, Zhu, Yongzhang, Qin, Jinhong, Cai, Chengsong, Zhao, Wei, Chang, Yung-Fu, Zhang, Yan, Guo, Xiaokui, He, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520481/
https://www.ncbi.nlm.nih.gov/pubmed/28536433
http://dx.doi.org/10.1038/emi.2017.16