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Oncogenic MCT-1 activation promotes YY1-EGFR-MnSOD signaling and tumor progression

Tumor cells often produce high levels of reactive oxygen species (ROS) and display an increased ROS scavenging system. However, the molecular mechanism that balances antioxidative and oxidative stress in cancer cells is unclear. Here, we determined that oncogenic multiple copies in T-cell malignancy...

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Detalles Bibliográficos
Autores principales: Tseng, H-Y, Chen, Y-A, Jen, J, Shen, P-C, Chen, L-M, Lin, T-D, Wang, Y-C, Hsu, H-L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520490/
https://www.ncbi.nlm.nih.gov/pubmed/28394354
http://dx.doi.org/10.1038/oncsis.2017.13