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CRB3 downregulation confers breast cancer stem cell traits through TAZ/β-catenin

The cancer stem cell (CSC) theory depicts a special population within the cancer mass that self-renew and sustain the cancer, even if the other cells were eliminated by therapies. How CSCs acquire these unique traits is still unclear. Crumbs homolog 3 (CRB3), a member of the CRB polarity complex, ha...

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Detalles Bibliográficos
Autores principales: Li, P, Wang, Y, Mao, X, Jiang, Y, Liu, J, Li, J, Wang, J, Wang, R, She, J, Zhang, J, Yang, J, Liu, Y, Liu, P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520500/
https://www.ncbi.nlm.nih.gov/pubmed/28436991
http://dx.doi.org/10.1038/oncsis.2017.24