Cargando…

Methylation of WNT target genes AXIN2 and DKK1 as robust biomarkers for recurrence prediction in stage II colon cancer

Stage II colon cancer (CC) still remains a clinical challenge with patient stratification for adjuvant therapy (AT) largely relying on clinical parameters. Prognostic biomarkers are urgently needed for better stratification. Previously, we have shown that WNT target genes AXIN2, DKK1, APCDD1, ASCL2...

Descripción completa

Detalles Bibliográficos
Autores principales: Kandimalla, R, Linnekamp, J F, van Hooff, S, Castells, A, Llor, X, Andreu, M, Jover, R, Goel, A, Medema, J P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520503/
https://www.ncbi.nlm.nih.gov/pubmed/28368388
http://dx.doi.org/10.1038/oncsis.2017.9