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Hepatocyte polyploidization and its association with pathophysiological processes

A characteristic cellular feature of the mammalian liver is the progressive polyploidization of the hepatocytes, where individual cells acquire more than two sets of chromosomes. Polyploidization results from cytokinesis failure that takes place progressively during the course of postnatal developme...

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Detalles Bibliográficos
Autores principales: Wang, Min-Jun, Chen, Fei, Lau, Joseph T Y, Hu, Yi-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520697/
https://www.ncbi.nlm.nih.gov/pubmed/28518148
http://dx.doi.org/10.1038/cddis.2017.167