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Cryptotanshinone inhibits human glioma cell proliferation in vitro and in vivo through SHP-2-dependent inhibition of STAT3 activation

Malignant gliomas (MGs) are one of the most common primary brain cancers in adults with a high mortality rate and relapse rate. Thus, finding better effective approaches to treat MGs has become very urgent. Here, we studied the effects of cryptotanshinone (CTS) on MGs in vitro and in vivo, and explo...

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Detalles Bibliográficos
Autores principales: Lu, Liang, Zhang, Sulin, Li, Cuixian, Zhou, Chun, Li, Dong, Liu, Peiqing, Huang, Min, Shen, Xiaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520699/
https://www.ncbi.nlm.nih.gov/pubmed/28492557
http://dx.doi.org/10.1038/cddis.2017.174