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BASP1 interacts with oestrogen receptor α and modifies the tamoxifen response

Tamoxifen binds to oestrogen receptor α (ERα) to elicit distinct responses that vary by cell/tissue type and status, but the factors that determine these differential effects are unknown. Here we report that the transcriptional corepressor BASP1 interacts with ERα and in breast cancer cells, this in...

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Detalles Bibliográficos
Autores principales: Marsh, Lindsey A, Carrera, Samantha, Shandilya, Jayasha, Heesom, Kate J, Davidson, Andrew D, Medler, Kathryn F, Roberts, Stefan GE
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520704/
https://www.ncbi.nlm.nih.gov/pubmed/28492543
http://dx.doi.org/10.1038/cddis.2017.179