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LncRNA HOTAIR regulates HIF-1α/AXL signaling through inhibition of miR-217 in renal cell carcinoma

Long non-coding RNA HOTAIR was regarded as an oncogene in multiple cancers. Previous studies have shown that HOTAIR is involved in the proliferation and tumorigenesis of renal carcinoma cells, while microRNA (miR)-217 functions as a tumor suppressor in renal cell carcinoma (Rcc). However, the underl...

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Detalles Bibliográficos
Autores principales: Hong, Quan, Li, Ou, Zheng, Wei, Xiao, Wen-zhen, Zhang, Lu, Wu, Di, Cai, Guang-yan, He, John Cijiang, Chen, Xiang-mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520706/
https://www.ncbi.nlm.nih.gov/pubmed/28492542
http://dx.doi.org/10.1038/cddis.2017.181