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Autophagy is essential for hearing in mice

Hearing loss is the most frequent sensory disorder in humans. Auditory hair cells (HCs) are postmitotic at late-embryonic differentiation and postnatal stages, and their damage is the major cause of hearing loss. There is no measurable HC regeneration in the mammalian cochlea, and the maintenance of...

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Detalles Bibliográficos
Autores principales: Fujimoto, Chisato, Iwasaki, Shinichi, Urata, Shinji, Morishita, Hideaki, Sakamaki, Yuriko, Fujioka, Masato, Kondo, Kenji, Mizushima, Noboru, Yamasoba, Tatsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520715/
https://www.ncbi.nlm.nih.gov/pubmed/28492547
http://dx.doi.org/10.1038/cddis.2017.194