Haploinsufficiency in the mitochondrial protein CHCHD4 reduces brain injury in a mouse model of neonatal hypoxia-ischemia

Mitochondria contribute to neonatal hypoxic-ischemic brain injury by releasing potentially toxic proteins into the cytosol. CHCHD4 is a mitochondrial intermembrane space protein that plays a major role in the import of intermembrane proteins and physically interacts with apoptosis-inducing factor (A...

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Detalles Bibliográficos
Autores principales: Sun, Yanyan, Li, Tao, Xie, Cuicui, Xu, Yiran, Zhou, Kai, Rodriguez, Juan, Han, Wei, Wang, Xiaoyang, Kroemer, Guido, Modjtahedi, Nazanine, Blomgren, Klas, Zhu, Changlian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520716/
https://www.ncbi.nlm.nih.gov/pubmed/28492551
http://dx.doi.org/10.1038/cddis.2017.196

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520716/
https://www.ncbi.nlm.nih.gov/pubmed/28492551
http://dx.doi.org/10.1038/cddis.2017.196

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