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A balance of Mad and Myc expression dictates larval cell apoptosis and adult stem cell development during Xenopus intestinal metamorphosis

The Myc/Mad/Max network has long been shown to be an important factor in regulating cell proliferation, death and differentiation in diverse cell types. In general, Myc–Max heterodimers activate target gene expression to promote cell proliferation, although excess of c-Myc can also induce apoptosis....

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Detalles Bibliográficos
Autores principales: Okada, Morihiro, Miller, Thomas C, Wen, Luan, Shi, Yun-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520718/
https://www.ncbi.nlm.nih.gov/pubmed/28492553
http://dx.doi.org/10.1038/cddis.2017.198