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DT-13 synergistically enhanced vinorelbine-mediated mitotic arrest through inhibition of FOXM1-BICD2 axis in non-small-cell lung cancer cells

Non-small-cell lung cancer (NSCLC) is the most commonly diagnosed malignant disease with the leading cause of cancer-related death. Combination treatment remains the major strategy in the clinical therapy of NSCLC. Vinorelbine (NVB), a semi-synthetic vinca alkaloid, is used for advanced and metastat...

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Detalles Bibliográficos
Autores principales: Li, Hongyang, Sun, Li, Li, Hang, Lv, Xiaodan, Semukunzi, Herve, Li, Ruiming, Yu, Jun, Yuan, Shengtao, Lin, Sensen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520732/
https://www.ncbi.nlm.nih.gov/pubmed/28542137
http://dx.doi.org/10.1038/cddis.2017.218