Functional screen analysis reveals miR-3142 as central regulator in chemoresistance and proliferation through activation of the PTEN-AKT pathway in CML

Chronic myeloid leukemia (CML) is caused by the constitutively active BCR-ABL tyrosine kinase. Although great progress has been made for improvement in clinical treatment during the past decades, it is common for patients to develop chemotherapy resistance. Therefore, further exploring novel therape...

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Detalles Bibliográficos
Autores principales: Zhao, Lifen, Shan, Yujia, Liu, Bing, Li, Yang, Jia, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520737/
https://www.ncbi.nlm.nih.gov/pubmed/28542127
http://dx.doi.org/10.1038/cddis.2017.223

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520737/
https://www.ncbi.nlm.nih.gov/pubmed/28542127
http://dx.doi.org/10.1038/cddis.2017.223

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