Aroclor1254 disrupts the blood–testis barrier by promoting endocytosis and degradation of junction proteins via p38 MAPK pathway

The blood–testis barrier (BTB) constituted by coexisting junction apparatus between Sertoli cells (SCs) plays an important role in spermatogenesis, which is a known target of various environmental toxicants. The commercial polychlorinated biphenyls mixture, Aroclor1254, has been shown to impair male...

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Detalles Bibliográficos
Autores principales: Jia, Xiaoyu, Xu, Ying, Wu, Weixing, Fan, Yunxia, Wang, Guoli, Zhang, Tianbiao, Su, Wenhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520738/
https://www.ncbi.nlm.nih.gov/pubmed/28542131
http://dx.doi.org/10.1038/cddis.2017.224

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520738/
https://www.ncbi.nlm.nih.gov/pubmed/28542131
http://dx.doi.org/10.1038/cddis.2017.224

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