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Activation of transient receptor potential vanilloid 4 involves in hypoxia/reoxygenation injury in cardiomyocytes

Transient receptor potential vanilloid 4 (TRPV4) is highly expressed in heart and vessels and can be activated during myocardial ischemia/reperfusion (I/R). Recently, we found that treatment with a selective TRPV4 antagonist HC-067047 significantly reduced infarct size, decreased troponin T levels a...

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Detalles Bibliográficos
Autores principales: Wu, Qiong-Feng, Qian, Cheng, Zhao, Ning, Dong, Qian, Li, Jing, Wang, Bin-Bin, Chen, Lei, Yu, Lixiu, Han, Bing, Du, Yi-Mei, Liao, Yu-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520739/
https://www.ncbi.nlm.nih.gov/pubmed/28542130
http://dx.doi.org/10.1038/cddis.2017.227