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Activation of transient receptor potential vanilloid 4 involves in hypoxia/reoxygenation injury in cardiomyocytes
Transient receptor potential vanilloid 4 (TRPV4) is highly expressed in heart and vessels and can be activated during myocardial ischemia/reperfusion (I/R). Recently, we found that treatment with a selective TRPV4 antagonist HC-067047 significantly reduced infarct size, decreased troponin T levels a...
Autores principales: | Wu, Qiong-Feng, Qian, Cheng, Zhao, Ning, Dong, Qian, Li, Jing, Wang, Bin-Bin, Chen, Lei, Yu, Lixiu, Han, Bing, Du, Yi-Mei, Liao, Yu-Hua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520739/ https://www.ncbi.nlm.nih.gov/pubmed/28542130 http://dx.doi.org/10.1038/cddis.2017.227 |
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