Phosphorylated CAV1 activates autophagy through an interaction with BECN1 under oxidative stress

CAV1/Caveolin1, an integral membrane protein, is involved in caveolae function and cellular signaling pathways. Here, we report that CAV1 is a positive regulator of autophagy under oxidative stress and cerebral ischemic injury. Treatment with hydrogen peroxide enhanced autophagy flux and caused the...

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Detalles Bibliográficos
Autores principales: Nah, Jihoon, Yoo, Seung-Min, Jung, Sunmin, Jeong, Eun Il, Park, Moonju, Kaang, Bong-Kiun, Jung, Yong-Keun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520747/
https://www.ncbi.nlm.nih.gov/pubmed/28542134
http://dx.doi.org/10.1038/cddis.2017.71

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520747/
https://www.ncbi.nlm.nih.gov/pubmed/28542134
http://dx.doi.org/10.1038/cddis.2017.71

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