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PAK4 regulates G6PD activity by p53 degradation involving colon cancer cell growth

The p21-activated kinase 4 (PAK4) is overexpressed in different cancers and promotes proliferation of cancer cells. Reprogramming of glucose metabolism is found in most cancer cells which in turn supports rapid proliferation. However, the relationship between PAK4 and glucose metabolism in cancer ce...

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Detalles Bibliográficos
Autores principales: Zhang, Xiumei, Zhang, Xia, Li, Yang, Shao, Yangguang, Xiao, Jianying, Zhu, Ge, Li, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520749/
https://www.ncbi.nlm.nih.gov/pubmed/28542136
http://dx.doi.org/10.1038/cddis.2017.85