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A Single Dose, Randomized, Controlled Proof-Of-Mechanism Study of a Novel Vasopressin 1a Receptor Antagonist (RG7713) in High-Functioning Adults with Autism Spectrum Disorder

The core symptoms of autism spectrum disorder (ASD) include impaired social communication, repetitive behaviors, and restricted interests. No effective pharmacotherapy for these core deficits exists. Within the domain of social communication, the vasopressin system is implicated in social cognition...

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Detalles Bibliográficos
Autores principales: Umbricht, Daniel, del Valle Rubido, Marta, Hollander, Eric, McCracken, James T, Shic, Frederick, Scahill, Lawrence, Noeldeke, Jana, Boak, Lauren, Khwaja, Omar, Squassante, Lisa, Grundschober, Christophe, Kletzl, Heidemarie, Fontoura, Paulo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520775/
https://www.ncbi.nlm.nih.gov/pubmed/27711048
http://dx.doi.org/10.1038/npp.2016.232