Cargando…

Assessment of simplified ratio-based approaches for quantification of PET [(11)C]PBR28 data

PURPOSE: Kinetic modelling with metabolite-corrected arterial plasma is considered the gold standard for quantification of [(11)C]PBR28 binding to the translocator protein (TSPO), since there is no brain region devoid of TSPO that can serve as reference. The high variability in binding observed usin...

Descripción completa

Detalles Bibliográficos
Autores principales: Matheson, Granville J., Plavén-Sigray, Pontus, Forsberg, Anton, Varrone, Andrea, Farde, Lars, Cervenka, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520824/
https://www.ncbi.nlm.nih.gov/pubmed/28733954
http://dx.doi.org/10.1186/s13550-017-0304-1