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Assessment of simplified ratio-based approaches for quantification of PET [(11)C]PBR28 data
PURPOSE: Kinetic modelling with metabolite-corrected arterial plasma is considered the gold standard for quantification of [(11)C]PBR28 binding to the translocator protein (TSPO), since there is no brain region devoid of TSPO that can serve as reference. The high variability in binding observed usin...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520824/ https://www.ncbi.nlm.nih.gov/pubmed/28733954 http://dx.doi.org/10.1186/s13550-017-0304-1 |