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Gene knockout of Zmym3 in mice arrests spermatogenesis at meiotic metaphase with defects in spindle assembly checkpoint

ZMYM3, a member of the MYM-type zinc finger protein family and a component of a LSD1-containing transcription repressor complex, is predominantly expressed in the mouse brain and testis. Here, we show that ZMYM3 in the mouse testis is expressed in somatic cells and germ cells until pachytene spermat...

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Detalles Bibliográficos
Autores principales: Hu, Xiangjing, Shen, Bin, Liao, Shangying, Ning, Yan, Ma, Longfei, Chen, Jian, Lin, Xiwen, Zhang, Daoqin, Li, Zhen, Zheng, Chunwei, Feng, Yanmin, Huang, Xingxu, Han, Chunsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520888/
https://www.ncbi.nlm.nih.gov/pubmed/28661483
http://dx.doi.org/10.1038/cddis.2017.228