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Nicotine protects rat hypoglossal motoneurons from excitotoxic death via downregulation of connexin 36
Motoneuron disease including amyotrophic lateral sclerosis may be due, at an early stage, to deficit in the extracellular clearance of the excitatory transmitter glutamate. A model of glutamate-mediated excitotoxic cell death based on pharmacological inhibition of its uptake was used to investigate...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520892/ https://www.ncbi.nlm.nih.gov/pubmed/28617431 http://dx.doi.org/10.1038/cddis.2017.232 |