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MicroRNA-195 prevents dendritic degeneration and neuron death in rats following chronic brain hypoperfusion

Impaired synaptic plasticity and neuron loss are hallmarks of Alzheimer’s disease and vascular dementia. Here, we found that chronic brain hypoperfusion (CBH) by bilateral common carotid artery occlusion (2VO) decreased the total length, numbers and crossings of dendrites and caused neuron death in...

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Detalles Bibliográficos
Autores principales: Chen, Xin, Jiang, Xue-Mei, Zhao, Lin-Jing, Sun, Lin-Lin, Yan, Mei-Ling, Tian, You, Zhang, Shuai, Duan, Ming-Jing, Zhao, Hong-Mei, Li, Wen-Rui, Hao, Yang-Yang, Wang, Li-Bo, Xiong, Qiao-Jie, Ai, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520902/
https://www.ncbi.nlm.nih.gov/pubmed/28569780
http://dx.doi.org/10.1038/cddis.2017.243