Cargando…
MicroRNA-195 prevents dendritic degeneration and neuron death in rats following chronic brain hypoperfusion
Impaired synaptic plasticity and neuron loss are hallmarks of Alzheimer’s disease and vascular dementia. Here, we found that chronic brain hypoperfusion (CBH) by bilateral common carotid artery occlusion (2VO) decreased the total length, numbers and crossings of dendrites and caused neuron death in...
Autores principales: | Chen, Xin, Jiang, Xue-Mei, Zhao, Lin-Jing, Sun, Lin-Lin, Yan, Mei-Ling, Tian, You, Zhang, Shuai, Duan, Ming-Jing, Zhao, Hong-Mei, Li, Wen-Rui, Hao, Yang-Yang, Wang, Li-Bo, Xiong, Qiao-Jie, Ai, Jing |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520902/ https://www.ncbi.nlm.nih.gov/pubmed/28569780 http://dx.doi.org/10.1038/cddis.2017.243 |
Ejemplares similares
-
MicroRNA-153 impairs presynaptic plasticity by blocking vesicle release following chronic brain hypoperfusion
por: Yan, Mei-Ling, et al.
Publicado: (2020) -
MicroRNA-195 prevents hippocampal microglial/macrophage polarization towards the M1 phenotype induced by chronic brain hypoperfusion through regulating CX3CL1/CX3CR1 signaling
por: Mao, Meng, et al.
Publicado: (2020) -
Metoprolol prevents neuronal dendrite remodeling in a canine model of chronic obstructive sleep apnea
por: Yang, Lin, et al.
Publicado: (2019) -
Chronic cerebral hypoperfusion induces vascular plasticity and hemodynamics but also neuronal degeneration and cognitive impairment
por: Jing, Zhen, et al.
Publicado: (2015) -
BDNF-mediates Down-regulation of MicroRNA-195 Inhibits Ischemic Cardiac Apoptosis in Rats
por: Hang, Pengzhou, et al.
Publicado: (2016)