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The role of oligodendrocyte precursor cells expressing the GPR17 receptor in brain remodeling after stroke

Following stroke-induced neuronal damage, quiescent oligodendrocyte precursors (OPCs) are activated to proliferate and later to differentiate to myelin-producing cells. GPR17, a receptor transiently expressed on early OPCs, has emerged as a target to implement stroke repair through stimulation of OP...

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Detalles Bibliográficos
Autores principales: Bonfanti, Elisabetta, Gelosa, Paolo, Fumagalli, Marta, Dimou, Leda, Viganò, Francesca, Tremoli, Elena, Cimino, Mauro, Sironi, Luigi, Abbracchio, Maria P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520912/
https://www.ncbi.nlm.nih.gov/pubmed/28594400
http://dx.doi.org/10.1038/cddis.2017.256