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EIF3D promotes gallbladder cancer development by stabilizing GRK2 kinase and activating PI3K-AKT signaling pathway

Recent evidence suggests that dysregulated eIF3d expression may be critical in various genetic disorders as well as cancer. In this study, we observed that EIF3d levels increased in gallbladder cancer (GBC) samples compared with non-tumor tissue. High eIF3d levels were associated with advanced tumor...

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Detalles Bibliográficos
Autores principales: Zhang, Fei, Xiang, Shanshan, Cao, Yang, Li, Maolan, Ma, Qiang, Liang, Haibin, Li, Huaifeng, Ye, Yuanyuan, Zhang, Yijian, Jiang, Lin, Hu, Yunping, Zhou, Jian, Wang, Xuefeng, Zhang, Yong, Nie, Lei, Liang, Xiao, Gong, Wei, Liu, Yingbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520919/
https://www.ncbi.nlm.nih.gov/pubmed/28594409
http://dx.doi.org/10.1038/cddis.2017.263