EGR-1/ASPP1 inter-regulatory loop promotes apoptosis by inhibiting cyto-protective autophagy

The decrease of ASPP1 (Apoptosis-Stimulating Protein of p53 1), a known p53 activator, has been linked to carcinogenesis and the cytotoxic resistance in various cancers, yet the underlying mechanisms of ASPP1 expression and its complex functions are not yet clear. Here, we report that ASPP1 forms an...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Kunming, Yu, Miao, Zhu, Yifu, Liu, Dong, Wu, Qiong, Hu, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520923/
https://www.ncbi.nlm.nih.gov/pubmed/28594407
http://dx.doi.org/10.1038/cddis.2017.268

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520923/
https://www.ncbi.nlm.nih.gov/pubmed/28594407
http://dx.doi.org/10.1038/cddis.2017.268

Ejemplares similares