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Titanium particle-induced osteogenic inhibition and bone destruction are mediated by the GSK-3β/β-catenin signal pathway

Wear debris-induced osteogenic inhibition and bone destruction are critical in the initiation of peri-prosthetic osteolysis. However, the molecular mechanism underlying this phenomenon is poorly understood. In this study, we analyzed the involvement of the GSK-3β/β-catenin signal pathway, which is i...

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Detalles Bibliográficos
Autores principales: Gu, Ye, Wang, Zhirong, Shi, Jiawei, Wang, Liangliang, Hou, Zhenyang, Guo, Xiaobin, Tao, Yunxia, Wu, Xiexing, Zhou, Wei, Liu, Yu, Zhang, Wen, Xu, Yaozeng, Yang, Huilin, Xue, Feng, Geng, Dechun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520930/
https://www.ncbi.nlm.nih.gov/pubmed/28617442
http://dx.doi.org/10.1038/cddis.2017.275