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Heme oxygenase-1 derived carbon monoxide suppresses Aβ(1–42) toxicity in astrocytes

Neurodegeneration in Alzheimer’s disease (AD) is extensively studied, and the involvement of astrocytes and other cell types in this process has been described. However, the responses of astrocytes themselves to amyloid β peptides ((Aβ; the widely accepted major toxic factor in AD) is less well unde...

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Detalles Bibliográficos
Autores principales: Hettiarachchi, Nishani T, Boyle, John P, Dallas, Mark L, Al-Owais, Moza M, Scragg, Jason L, Peers, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520931/
https://www.ncbi.nlm.nih.gov/pubmed/28617444
http://dx.doi.org/10.1038/cddis.2017.276