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AQP9-induced cell cycle arrest is associated with RAS activation and improves chemotherapy treatment efficacy in colorectal cancer

Aquaporin-9 (AQP9) expression is associated with arsenic sensitivity in leukemia cells. However, the role of AQP9 in regulating tumor sensitivity to adjuvant chemotherapy in colorectal cancer (CRC) has not been elucidated. In this study, we demonstrated that AQP9 can serve as an independent predicti...

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Detalles Bibliográficos
Autores principales: Huang, Dandan, Feng, Xingzhi, Liu, Yiting, Deng, Yanhong, Chen, Hao, Chen, Daici, Fang, Lekun, Cai, Yue, Liu, Huanliang, Wang, Lei, Wang, Jianping, Yang, Zihuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520935/
https://www.ncbi.nlm.nih.gov/pubmed/28640255
http://dx.doi.org/10.1038/cddis.2017.282