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KDM2B, an H3K36-specific demethylase, regulates apoptotic response of GBM cells to TRAIL
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) can selectively kill tumor cells. TRAIL resistance in cancers is associated with aberrant expression of the key components of the apoptotic program. However, how these components are regulated at the epigenetic level is not understood....
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520939/ https://www.ncbi.nlm.nih.gov/pubmed/28661478 http://dx.doi.org/10.1038/cddis.2017.288 |