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KDM2B, an H3K36-specific demethylase, regulates apoptotic response of GBM cells to TRAIL

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) can selectively kill tumor cells. TRAIL resistance in cancers is associated with aberrant expression of the key components of the apoptotic program. However, how these components are regulated at the epigenetic level is not understood....

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Detalles Bibliográficos
Autores principales: Kurt, Ibrahim Cagri, Sur, Ilknur, Kaya, Ezgi, Cingoz, Ahmet, Kazancioglu, Selena, Kahya, Zeynep, Toparlak, Omer Duhan, Senbabaoglu, Filiz, Kaya, Zeynep, Ozyerli, Ezgi, Karahüseyinoglu, Sercin, Lack, Nathan A, Gümüs, Zeynep H, Onder, Tamer T, Bagci-Onder, Tugba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520939/
https://www.ncbi.nlm.nih.gov/pubmed/28661478
http://dx.doi.org/10.1038/cddis.2017.288