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Ubiquitin-dependent regulation of Cdc42 by XIAP

Rho GTPases control fundamental cellular processes and Cdc42 is a well-studied member of the family that controls filopodia formation and cell migration. Although the regulation of Cdc42 activity by nucleotide binding is well documented, the mechanisms driving its proteostasis are not clear. Here, w...

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Detalles Bibliográficos
Autores principales: Murali, Arun, Shin, Jaeyoung, Yurugi, Hajime, Krishnan, Aswini, Akutsu, Masato, Carpy, Alejandro, Macek, Boris, Rajalingam, Krishnaraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520948/
https://www.ncbi.nlm.nih.gov/pubmed/28661476
http://dx.doi.org/10.1038/cddis.2017.305