Interferon-γ derived from cytotoxic lymphocytes directly enhances their motility and cytotoxicity

Interferon gamma (IFNγ) is a key moderator of cell-mediated immunity with diverse, mainly pro-inflammatory actions on immunocytes and target tissue. Recent studies have shown it may enhance anti-tumor and antiviral effects of CD8 T cells. Here we investigate the mechanisms by which IFNγ mediates CD8...

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Detalles Bibliográficos
Autores principales: Bhat, Purnima, Leggatt, Graham, Waterhouse, Nigel, Frazer, Ian H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520949/
https://www.ncbi.nlm.nih.gov/pubmed/28569770
http://dx.doi.org/10.1038/cddis.2017.67

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520949/
https://www.ncbi.nlm.nih.gov/pubmed/28569770
http://dx.doi.org/10.1038/cddis.2017.67

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