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Interferon-γ derived from cytotoxic lymphocytes directly enhances their motility and cytotoxicity
Interferon gamma (IFNγ) is a key moderator of cell-mediated immunity with diverse, mainly pro-inflammatory actions on immunocytes and target tissue. Recent studies have shown it may enhance anti-tumor and antiviral effects of CD8 T cells. Here we investigate the mechanisms by which IFNγ mediates CD8...
Autores principales: | Bhat, Purnima, Leggatt, Graham, Waterhouse, Nigel, Frazer, Ian H |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5520949/ https://www.ncbi.nlm.nih.gov/pubmed/28569770 http://dx.doi.org/10.1038/cddis.2017.67 |
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