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A deep convolutional neural network approach to single-particle recognition in cryo-electron microscopy

BACKGROUND: Single-particle cryo-electron microscopy (cryo-EM) has become a mainstream tool for the structural determination of biological macromolecular complexes. However, high-resolution cryo-EM reconstruction often requires hundreds of thousands of single-particle images. Particle extraction fro...

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Detalles Bibliográficos
Autores principales: Zhu, Yanan, Ouyang, Qi, Mao, Youdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5521087/
https://www.ncbi.nlm.nih.gov/pubmed/28732461
http://dx.doi.org/10.1186/s12859-017-1757-y