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A deep convolutional neural network approach to single-particle recognition in cryo-electron microscopy
BACKGROUND: Single-particle cryo-electron microscopy (cryo-EM) has become a mainstream tool for the structural determination of biological macromolecular complexes. However, high-resolution cryo-EM reconstruction often requires hundreds of thousands of single-particle images. Particle extraction fro...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5521087/ https://www.ncbi.nlm.nih.gov/pubmed/28732461 http://dx.doi.org/10.1186/s12859-017-1757-y |